Emeritus Faculty

  • Robert Blanks
  • Ralph Bradshaw
  • James Fallon
  • Roland Giolli
  • Leonard Kitzes
  • Charles Ribak
  • John Swett
Decorative button

Scientists: Anne Calof, Ph.D.

Dr. Anne Calof

Professor:

Anatomy & Neurobiology
Developmental & Cell Biology
Center for Complex Biological Systems

Decorative Icon Calof Home Page     Decorative Icon Biography     Decorative Icon Research

Research Focus

Working to understand: Systems Biology of Neural Stem Cells and Human Developmental Disorders

Scientific Focus: Lineage dynamics of neural stem cells; gene networks underlying neurodevelopmental disorders.

Decorative Icon RECENT PUBLICATIONS ON PUBMED

Selected Publications

Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T.
(2012) What does the concept of the stem cell niche really mean today? BMC Biol. 2012 Mar 9;10:19: pp 1-15.

Santos R, Wu J, Hamilton JA, Pinter R, Hindges R, Calof AL.
(2012) Restoration of retinal development in Vsx2 deficient mice by reduction of Gdf11 levels. Adv Exp Med Biol. Adv. Exp. Med. Biol. 723: 671-677. 

Muto A, Calof AL, Lander AD, Schilling TF.
(2011) Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome. PLoS Biol.Oct;9(10):e1001181. Epub 2011 Oct 25. (comment: PLoS Biol. 2011 Oct;9(10):e1001180)

Gokoffski KK, Wu HH, Beites CL, Kim J, Kim EJ, Matzuk MM, Johnson JE, Lander AD, Calof AL.
(2011) Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development, 138: pp. 4131-4142.

Chien R, Zeng W, Kawauchi S, Bender MA, Santos R, Gregson HC, Schmiesing JA, Newkirk DA, Kong X, Ball AR Jr, Calof AL, Lander AD, Groudine MT, Yokomori K.
(2011) Cohesin Mediates Chromatin Interactions That Regulate Mammalian {beta}-globin Expression. J Biol Chem. 286:DOI 10.1074

Chou CS, Lo WC, Gokoffski KK, Zhang YT, Wan FY, Lander AD, Calof AL, Nie Q.
(2010) Spatial dynamics of multistage cell lineages in tissue stratification. Biophys J. 99 (10): 3145-3154.

Gokoffski KK, Kawauchi S, Wu HH, Santos R, Hollenbeck PLW, Lander AD, Calof AL.
(2010) Feedback Regulation of Neurogenesis in the Mammalian Olfactory Epithelium: New Insights from Genetics and Systems Biology. In: Menini A, editor. The Neurobiology of Olfaction. (A. Menini, Ed.) CRC Press, pp. 241-265.

Kawauchi, S*, Calof, AL*, Santos, R., Lopez-Burks, ME, Young, CM, Hoang, MP, Chua, A., Lao, T., Lechner, MS, Daniel, JA, Nussenzweig, A., Kitzes, L., Yokomori, K., Hallgrimsson, B. and Lander, A.D.
(2009) Multiple organ system defects and transcriptional dysregulation in a mouse model of Cornelia de Lange Syndrome. PLoS Genetics, 5(9): e1000650. Doi:10.1371/journalLpgen.1000650. (* = Co-first authors) .

Beites, CL, Hollenbeck, PLW, Kim, J, Lovell-Badge, R, Lander, AD, and Calof, AL
(2009) Follistatin modulates a BMP autoregulatory loop to control size and patterning of sensory domains in the developing tongue. Development, 136: 2187-2197

Kawauchi, S., Kim, J., Santos, R., Wu, H. H., Lander, A. D. and Calof, A. L.
(2009). Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development 136, 1453-64.

Contact Information

E-mail:

alcalof@uci.edu

Phone:

949-824-4616,
949-824-5745

FAX:

949-824-1104

Address:

Anatomy & Neurobiology,
2300 Bio Sci III,
UCI School of Medicine,
Irvine, CA 92697-1275

The Lab

Shimako Kawauchi
Project Scientist
Xu Wang
Postdoctoral Researcher
Rosie Santos
Postdoctoral Researcher
Samir Qurashi
Research Assistant
Mona Yazdi
Research Assistant

Supporting This Work

Donations to labs may be applied in many ways: from costs for experiments to support for a student's stipend.

Join us in becoming a part of scientific history, by supporting the work of this lab.

Learn more by contacting Sara Johnson, sara.johnson@uci.edu, or by visiting our Get Involved Page, where you can donate online.