Scientists: Anne Calof, Ph.D.

Research Focus

Working to understand: Systems Biology of Neural Stem Cells and Human Developmental Disorders

Scientific Focus: Lineage dynamics of neural stem cells; gene networks underlying neurodevelopmental disorders.

RECENT PUBLICATIONS ON PUBMED

Selected Publications

Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T.
(2012) What does the concept of the stem cell niche really mean today? BMC Biol. 2012 Mar 9;10:19: pp 1-15.

Santos R, Wu J, Hamilton JA, Pinter R, Hindges R, Calof AL.
(2012) Restoration of retinal development in Vsx2 deficient mice by reduction of Gdf11 levels. Adv Exp Med Biol. Adv. Exp. Med. Biol. 723: 671-677. 

Muto A, Calof AL, Lander AD, Schilling TF.
(2011) Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome. PLoS Biol.Oct;9(10):e1001181. Epub 2011 Oct 25. (comment: PLoS Biol. 2011 Oct;9(10):e1001180)

Gokoffski KK, Wu HH, Beites CL, Kim J, Kim EJ, Matzuk MM, Johnson JE, Lander AD, Calof AL.
(2011) Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development, 138: pp. 4131-4142.

Chien R, Zeng W, Kawauchi S, Bender MA, Santos R, Gregson HC, Schmiesing JA, Newkirk DA, Kong X, Ball AR Jr, Calof AL, Lander AD, Groudine MT, Yokomori K.
(2011) Cohesin Mediates Chromatin Interactions That Regulate Mammalian {beta}-globin Expression. J Biol Chem. 286:DOI 10.1074

Chou CS, Lo WC, Gokoffski KK, Zhang YT, Wan FY, Lander AD, Calof AL, Nie Q.
(2010) Spatial dynamics of multistage cell lineages in tissue stratification. Biophys J. 99 (10): 3145-3154.

Gokoffski KK, Kawauchi S, Wu HH, Santos R, Hollenbeck PLW, Lander AD, Calof AL.
(2010) Feedback Regulation of Neurogenesis in the Mammalian Olfactory Epithelium: New Insights from Genetics and Systems Biology. In: Menini A, editor. The Neurobiology of Olfaction. (A. Menini, Ed.) CRC Press, pp. 241-265.

Kawauchi, S*, Calof, AL*, Santos, R., Lopez-Burks, ME, Young, CM, Hoang, MP, Chua, A., Lao, T., Lechner, MS, Daniel, JA, Nussenzweig, A., Kitzes, L., Yokomori, K., Hallgrimsson, B. and Lander, A.D.
(2009) Multiple organ system defects and transcriptional dysregulation in a mouse model of Cornelia de Lange Syndrome. PLoS Genetics, 5(9): e1000650. Doi:10.1371/journalLpgen.1000650. (* = Co-first authors) .

Beites, CL, Hollenbeck, PLW, Kim, J, Lovell-Badge, R, Lander, AD, and Calof, AL
(2009) Follistatin modulates a BMP autoregulatory loop to control size and patterning of sensory domains in the developing tongue. Development, 136: 2187-2197

Kawauchi, S., Kim, J., Santos, R., Wu, H. H., Lander, A. D. and Calof, A. L.
(2009). Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development 136, 1453-64.