Emeritus Faculty

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Scientists: Robert Hunt, Ph.D.

Dr. Robert Hunt and lab

Assistant Professor:

Anatomy & Neurobiology

Decorative Icon Hunt Home Page     Decorative Icon Biography     Decorative Icon Research    Decorative Icon Hunt Lab

Research Focus

Working to understand: epilepsy, disorders of cortical development, traumatic brain injury.

Scientific Focus: development and function of the forebrain.

Decorative Icon RECENT PUBLICATIONS ON PUBMED

Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JLR. NPAS1 Represses the Generation of Specific Subtypes of Cortical Interneurons, Neuron, Volume 84, Issue 5, 3 December 2014, Pages 940-953, ISSN 0896-6273, http://dx.doi.org/10.1016/j.neuron.2014.10.040.

Toyooka K, Wachi T, Hunt RF, Baraban SC, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain, J. Neuroscience. 2014; 34(36): 12168-12181. doi:10.1523/JNEUROSCI.2513-13.2014.

Vogt D, Hunt RF, Mandal S, Sandberg M, Silberberg SN, Nagasawa T, Yang Z, Baraban SC, Rubenstein JLR. Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position, Neuron. 2014; 82(2): 350-364. http://dx.doi.org/10.1016/j.neuron.2014.02.030.

Hunt RF, Boychuk JA, Smith BN. Neural circuit mechanisms of posttraumatic epilepsy, Frontiers in Cellular Neuroscience. 2013; 7: 89. http://dx.doi.org/10.3389/fncel.2013.00089.

Hunt RF, Girskis KM, Rubenstein JL, Alvarez-Buylla A, Baraban SC. GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior, Nature Neuroscience. 2013; 16: 692-697. doi:10.1038/nn.3392.

Hunt RF, Baraban SC. The devil is in the details: Stem cells for the treatment of epilepsy, Epilepsy Currents. 2012; 32(1):46–61. http://dx.doi.org/10.5698/1535-7511-12.6.213.

Hunt RF, Dinday MT, Hindle-Katel W, Baraban SC. LIS1 deficiency promotes dysfunctional synaptic integration of granule cells generated in the developing and adult dentate gyrus, J. Neuroscience. 2012; 32(37):12862–12875. doi:10.1523/JNEUROSCI.1286-12.2012.

Hunt RF, Hortopan GA, Gillespie A, Baraban SC. A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors, Experimental Neurology. 2012; 237(1): 199-206. doi:10.1016/j.expneurol.2012.06.013.

Hunt RF, Haselhorst LA, Bach EC, Rios-Pelier J, Schoch KM, Scheff SW, Saatman KE, and Smith BN. Posttrauamtic mossy fiber sprouting is related to cortical damage in three mouse strains, Epilepsy Research. 2012; 99: 167-170. doi:10.1016/j.eplepsyres.2011.10.011.

Hunt RF, Scheff SW, Smith BN. Synaptic reorganization of inhibitory hilar interneuron circuitry after traumatic brain injury in mice, J. Neuroscience. 2011; 31(18): 6880-90. doi:10.1523/JNEUROSCI.0032-11.2011.

Hunt RF, Scheff SW, Smith BN. Regionally localized recurrent excitation in the dentate gyrus of a cortical contusion model of posttraumatic epilepsy, J. Neurophysiology. 2010; 103: 1490-1500. doi:10.1152/jn.00957.2009.

Hunt RF, Scheff SW, Smith BN. Posttraumatic epilepsy after controlled cortical impact injury in mice, Experimental Neurology. 2009; 215: 243-252. doi:10.1016/j.expneurol.2008.10.005.

Contact Information

E-mail:

robert.hunt@uci.edu

Phone:

949-824-7079

Address:

110, Irvine Hall,
University of California
Irvine, California 92697

The Lab

Saad Abbasi, Ph.D.
Postdoctoral Scholar,
Sunyoung Lee
Undergraduate Student,
Fernanda Pacheco
Visiting Student

Supporting This Work

Donations to labs may be applied in many ways: from costs for experiments to support for a student's stipend.

Join us in becoming a part of scientific history, by supporting the work of this lab.

Learn more by contacting Pamela Foster, pamela.foster@uci.edu, or by visiting our Get Involved Page, where you can donate online.