Anatomy & Neurobiology
Working to understand: drug addiction
Scientific Focus: development of the nervous system, with a particular focus on the development of neurotransmitter systems and the effects of drugs of abuse on nervous system development.
Toll L, Zaveri NT, Polgar WE, Jiang F, Khroyan TV, Zhou W, Xie XS, Stauber GB, Costello MR,
AT-1001:a high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self- administration in rats. Neuropsychopharmacology. 2012 May;37(6):1367-76. doi: 10.1038/npp.2011.322. Epub 2012 Jan 25.
Lotfipour S, Arnold MM, Hogenkamp DJ, Gee KW, Belluzzi JD,
The monoamine oxidase (MAO) inhibitor tranylcypromine enhances nicotine self-administration in rats through a mechanism independent of MAO inhibition. Neuropharmacology. 2011 Jul-Aug;61(1-2):95-104. Epub 2011 Mar 23.
Dao JM, McQuown SC, Loughlin SE, Belluzzi JD,
Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism. Neuropsychopharmacology. 2011 Jun;36(7):1319-31. Epub 2011 Mar 16.
Villégier AS, Belluzzi JD,
Serotonergic mechanism underlying tranylcypromine enhancement of nicotine self-administration. Synapse. 2011 Jun;65(6):479-89. doi: 10.1002/syn.20864. Epub 2010 Nov 9.
Wei J, Wang J, Dwyer JB, Mangold J, Cao J,
Gestational nicotine treatment modulates cell death/survival-related pathways in the brains of adolescent female rats.
Int J Neuropsychopharmacol. 2010 Apr 29:1-16.
Cao J, Belluzzi JD, Loughlin SE, Dao JM, Chen Y,
Locomotor and stress responses to nicotine differ in adolescent and adult rats. Pharmacol Biochem Behav. 2010 Apr 25.
Gehricke JG, Potkin SG,
Nicotine-induced brain metabolism associated with anger provocation. Behav Brain Funct. 2009 Apr 24;5:19.
Cao J, Dwyer JB, Mangold JE, Wang J, Wei J,
Modulation of cell adhesion systems by prenatal nicotine exposure in limbic brain regions of adolescent female rats. Int J Neuropsychopharmacol. 2010 Mar 3:1-18.
Villégier AS, Gallager B, Heston J, Belluzzi JD,
Age influences the effects of nicotine and monoamine oxidase inhibition on mood-related behaviors in rats. Psychopharmacology (Berl). 2010 Jan 14.
McQuown SC, Dao JM, Belluzzi JD,
Age-dependent effects of low-dose nicotine treatment on cocaine-induced behavioral plasticity in rats. Psychopharmacology (Berl). 2009 Nov;207(1):143-52.
Dept of Pharmacology,
367 Med Surge II,
University of California,
Irvine, California 92697-4625
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