Working to understand:
Hilgenberg LG, Pham B, Ortega M, Walid S, Kemmerly T, O'Dowd DK,
2009. Agrin regulation of alpha 3 sodium potassium ATPase activity modulates cardiac myocyte contraction. J Biol Chem, 2009 Apr 16. [Epub ahead of print].
Chen, K., A. Neu, A. L. Howard, C. Foldy, J. Echegoyen, L. Hilgenberg,
2007. Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures. J Neurosci. 27:46-58.
Tan, Z., X. Sun, F. S. Hou, H. W. Oh, L. G. Hilgenberg, E. M. Hol, F. W. van Leeuwen,
2007. Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. Cell Death Differ. 14:1721-1732.
Hilgenberg, L.G., Su, H., Gu, H., O'Dowd D. K., and
(2006). α3Na+/K+-ATPase is a neuronal receptor for agrin. Cell 125, 359-369.
Hilgenberg, L.G. and
2004. Agrin signaling in cortical neurons is mediated by a tyrosine kinase-dependent increase in intracellular Ca(2+) that engages both CaMKII and MAPK signal pathways. J. Neurobiol. 61: 289-300.
Hoover, C. L., L. G. W. Hilgenberg, et al.
2003. The COOH-terminal domain of agrin signals via a synaptic receptor in CNS neurons. J. Cell Biol. 161: 923-932.
Hilgenberg, L.G.W., K.D. Ho, D. Lee, D.K. O'Dowd, and
2002. Agrin regulates neuronal responses to excitatory neurotransmitters in vitro and in vivo. Mol. Cell. Neurosci. 19:97-110.
Dep't Anatomy & Neurobiology,
School of Medicine,
University of California,
Irvine, CA 92697-1280
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