Anatomy & Neurobiology
We are interested in how brain cells communicate with each other and how the communication changes after fever-induced seizures in early childhood and after head injury. Our general goal is to understand how neuronal networks function and dysfunction, in order to discover new therapies to prevent epilepsy.
Postdoctoral fellows and graduate students in the lab employ a variety of cutting-edge experimental and computational modeling techniques to understand normal and epilepsy-related plasticity in neuronal networks. The techniques include paired patch clamp recordings from immunocytochemically identified neurons from rodent hippocampal slices, combined with powerful spinning-disk imaging and biologically realistic large-scale computational modeling methods.