Emeritus Faculty

  • Robert Blanks
  • Ralph Bradshaw
  • James Fallon
  • Roland Giolli
  • Leonard Kitzes
  • Charles Ribak
  • Richard Robertson
  • Martim Smith
  • John Swett
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Scientists: Ivan Soltesz, Ph.D.

Dr. Ivan Soltesz

Adjunct Professor:

Anatomy & Neurobiology

 

Research Description and Approach

We are interested in how brain cells communicate with each other and how the communication changes after fever-induced seizures in early childhood and after head injury. Our general goal is to understand how neuronal networks function and dysfunction, in order to discover new therapies to prevent epilepsy.

Postdoctoral fellows and graduate students in the lab employ a variety of cutting-edge experimental and computational modeling techniques to understand normal and epilepsy-related plasticity in neuronal networks. The techniques include paired patch clamp recordings from immunocytochemically identified neurons from rodent hippocampal slices, combined with powerful spinning-disk imaging and biologically realistic large-scale computational modeling methods.

The Work

Fast-spiking interneurons Firing pattern of Parvalbumin-positive interneuron in the CA1 region of the rat hippocampus Parvalbumin-positive interneurons in the  CA1 region of the rat hippocampus