1977 | B.A., Classical Studies | University of Naples, Italy |
1982 | Pharm. D., magna cum laude | University of Naples, Italy |
1988 | Ph.D., Pharmacology | Columbia University, New York |
1987-1988 | Postdoctoral Fellow | Columbia University, New York |
1988-1990 | Postdoctoral Associate | Rockefeller University, New York |
1990-1995 | Chargé de Recherche (90-92), Directeur de Recherche | INSERM; Paris, France |
1995-1998 | Senior Fellow and Lab Head, The Neurosciences Institute | San Diego, California |
1998-2000 | Associate Professor, Pharmacology | University of California, Irvine |
2000-2007 | Founder, Kadmus Pharmaceuticals, Inc. | Irvine, CA |
2000-2012 | Professor, Department of Pharmacology | University of California, Irvine |
2001-Present | Fellow, Center for the Neurobiology of Learning & Memory | University of California, Irvine |
2005-Present | Professor, Department of Biological Chemistry | University of California, Irvine |
2005-Present | Louise Turner Arnold Chair in the Neurosciences | University of California, Irvine |
2007-Present | Director, Drug Discovery & Development | Italian Institute of Technology, Genoa, Italy |
2012-Present | Founder, Thesan Pharmaceuticals Inc. | Irvine, California |
2012-Present | Professor, Department of Anatomy & Neurobiology | University of California, Irvine |
2015-Present | Founder, Neokera Pharmaceuticals LLC | Irvine, CA |
- D. Piomelli, A. Volterra, N. Dale, S. Siegelbaum, E.R. Kandel, J.H. Schwartz and F. Belardetti, 1987. Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature 328, 38-43. PMID: 2439918
- D. Piomelli and P. Greengard, 1990. Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signaling. Trends Pharmacol Sci 11, 367-373. PMID: 2122564
- V. Di Marzo, A. Fontana, H. Cadas, S. Schinelli, G. Cimino, J.C. Schwartz and D. Piomelli, 1994. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 372, 686-691. PMID: 7990962
- N. Stella, P. Schweitzer and D. Piomelli, 1997. A second endogenous cannabinoid that modulates long-term potentiation. Nature 388, 773-778. PMID: 9285589
- A. Calignano, G. La Rana, A. Giuffrida and D. Piomelli, 1998. Control of pain initiation by endogenous cannabinoids. Nature 394, 277-281. PMID: 9685157
- A. Giuffrida, L.H. Parsons, T.M. Kerr, F. Rodríguez de Fonseca, M. Navarro and D. Piomelli, 1999. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nature Neuroscience 2, 358-363. PMID: 10204543
- F. Rodríguez de Fonseca, M. Navarro, R. Gómez, L. Escuredo, F. Nava, J. Fu, E. Murillo-Rodríguez, A. Giuffrida, J. LoVerme, S. Gaetani, S. Kathuria, C. Gall and D. Piomelli, 2001. An anorexic lipid mediator regulated by feeding. Nature 414, 209-212. PMID: 11700558
- T.P. Dinh, D. Carpenter, F.M. Leslie, T.F. Freund, I. Katona, S.L. Sensi, S. Kathuria and D. Piomelli, 2002. Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci USA 99, 10819-10824. PMCID: PMC125056
- J. Fu, S. Gaetani, F. Oveisi, J. LoVerme, A. Serrano, F. Rodríguez de Fonseca, A. Rosengarth, H. Luecke, B. Di Giacomo, G. Tarzia and D. Piomelli, 2003. Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-a. Nature 425, 90-93. PMID: 12955147
- S. Kathuria, S. Gaetani, D. Fegley, F. Valiño, A. Duranti, A. Tontini, M. Mor, G. Tarzia, G. La Rana, A. Calignano, A. Giustino, M. Tattoli, M. Palmery, V. Cuomo and D. Piomelli, 2003. Modulation of anxiety through blockade of anandamide hydrolysis. Nature Medicine 9, 76-81. PMID: 12461523
- A.G. Hohmann, R.L. Suplita II, N.M. Bolton, M.H. Neely, D. Fegley, R. Mangieri, J.F. Krey, J.M. Walker, P.V. Holmes, J.D. Crystal, A. Duranti, A. Tontini, M. Mor, G. Tarzia and D. Piomelli, 2005. An endocannabinoid mechanism for stress-induced analgesia. Nature 435, 1108-1112. PMID: 15973410
- C. Solorzano, C. Zhu, N. Battista, G. Astarita, A. Lodola, S. Rivara, M. Mor, R. Russo, M. Maccarrone, F. Antonietti, A. Duranti, A. Tontini, S. Cuzzocrea, G. Tarzia and D. Piomelli, 2009. Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proc Natl Acad Sci USA 106, 20966-20971. PMCID: PMC2791595
- J.R. Clapper, G. Moreno-Sanz, R. Russo, A. Guijarro, F. Vacondio, A. Duranti, A. Tontini, S. Sanchini, N.R. Sciolino, J.M. Spradley, A.G. Hohmann, A. Calignano, M. Mor, G. Tarzia and D. Piomelli, 2010. Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. Nature Neuroscience 13, 1265-1270. PMCID: PMC3260554
- D. Pizzirani, A. Bach, N. Realini, A. Armirotti, L. Mengatto, I. Bauer, S. Girotto, C. Pagliuca, M. De Vivo, M. Summa, A. Ribeiro and D. Piomelli, 2015. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase. Angewandte Chemie 54, 485-489. PMID: 25395373
Link to Complete List of Published Work in NCBI PubMed My Bibliography Page: http://www.ncbi.nlm.nih.gov/sites/myncbi/daniele.piomelli.1/bibliography/40700007/public/?sort=date&direction=descending